Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29279562 | 0.81 | MAPT (0.39) | MAPTALOX5ARCYP1A2CYP3A4 | |
| SCHEMBL29279571 | 0.80 | MAPT (0.39) | MAPTALOX5AR | |
| SCHEMBL20970965 | 0.79 | HTR2A (0.55) | MAPTARCYP1A2CYP3A4 | |
| SCHEMBL27002043 | 0.77 | USP2 (0.43) | PPARGPPARA | |
| SCHEMBL27002131 | 0.75 | HTR2A (0.54) | MAPTCYP1A2CYP3A4 | |
| SCHEMBL28003037 | 0.73 | ATM (0.59) | CYP1A2CYP3A4 | |
| SCHEMBL29814853 | 0.72 | MEN1 (0.47) | — | |
| SCHEMBL5293465 | 0.71 | MAOA (0.54) | — | |
| SCHEMBL27002104 | 0.70 | SIGMAR1 (0.39) | AR | |
| SCHEMBL20970884 | 0.70 | HTR2A (0.58) | ARCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642379-A | Phenylalkylamines and methods of making and using the same | 吉尔伽美什制药公司 | 2024-03-01 | — | — | CN | disclosed |