SCHEMBL20970965

SCHEMBL20970965

CCCCSc1c(OC)cc(CCN)cc1OC

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 9/20 0.55
▸ HTR2C P28335 3/20 0.53
▸ HTR2B P41595 3/20 0.53
▸ KDM4E B2RXH2 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ TAAR1 Q96RJ0 3/20 0.45
▸ TSHR P16473 2/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ LMNA P02545 2/20 0.44
▸ GLA P06280 2/20 0.44
▸ MAPT P10636 1/20 0.43
▸ CYP1A2 P05177 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ NFKB1 P19838 1/20 0.41
▸ AR P10275 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ APEX1 P27695 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27002131 0.95 HTR2A (0.54) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL20970884 0.90 HTR2A (0.58) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL26056043 0.88 HTR2A (0.59) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL27002187 0.86 HTR2A (0.58) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL27002101 0.85 HTR2A (0.57) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL27002147 0.85 HTR2A (0.52) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL27002071 0.84 HTR2A (0.51) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL20970855 0.83 HTR2A (0.61) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL27002138 0.82 HTR2A (0.61) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL27002059 0.81 HTR2A (0.59) HTR2AHTR2CHTR2BKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353808-A1 5-METHOXYMETHYL AND 5-HYDROXYMETHYL PHENETHYLAMINES 2A BIOSCIENCES, INC. 2025-11-20 — — US disclosed
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same Kuleon, LLC (US) 2025-10-14 — — US disclosed
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME KULEON LLC (US) 2025-09-11 — — US disclosed
WO-2025137730-A1 N-SUBSTITUTED TRYPTAMINES AND N-SUBSTITUTED LYSERGAMIDES AND THEIR USE AS THERAPEUTIC AGENTS ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. (US) 2025-06-26 — — WO disclosed
WO-2025030181-A1 CRYSTALLINE POLYMORPHS OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE (2C-B) ARCADIA MEDICINE, INC. (US) 2025-02-06 — — WO disclosed
US-12012380-B1 Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators KULEON LLC (US) 2024-06-18 — — US disclosed
US-20240190819-A1 Neuroplastogens and Non-Hallucinogenic Serotonin 5-HT2A Receptor Modulators KULEON LLC (US) 2024-06-13 — — US disclosed
US-20240166618-A1 PHENALKYLAMINES AND METHODS OF MAKING AND USING THE SAME GILGAMESH PHARMACEUTICALS, INC. (US) 2024-05-23 — — US disclosed
US-20240124397-A1 METHODS OF TREATING PSYCHOLOGICAL DISORDERS THROUGH THE ADMINISTRATION OF SEROTONIN 5-HT2C RECEPTOR MODULATORS Kuleon, LLC (US) 2024-04-18 — — US disclosed
WO-2024077203-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2024-04-11 — — WO disclosed
US-20230265045-A1 PHENALKYLAMINES AND METHODS OF TREATING MOOD DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2023-08-24 — — US disclosed
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR Kuleon, LLC (US) 2023-08-17 — — US disclosed
WO-2023122135-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-06-29 — — WO disclosed
WO-2023122320-A1 POLYPODAL SEROTONERGIC COMPOUNDS AND PRODRUGS OF SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS KULEON LLC (US) 2023-06-29 — — WO disclosed
WO-2023023298-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-23 — — WO disclosed
WO-2022192781-A1 PHENALKYLAMINES AND METHODS OF MAKING AND USING THE SAME GILGAMESH PHARMACEUTICALS, INC. (US) 2022-09-15 — — WO disclosed
WO-2022115798-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE WESANA HEALTH INC. (US) 2022-06-02 — — WO disclosed
WO-2022115796-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL CONDITIONS WESANA HEALTH INC. (US) 2022-06-02 — — WO disclosed
WO-2022006186-A1 PHENALKYLAMINES AND METHODS OF TREATING MOOD DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2022-01-06 — — WO disclosed
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CAAMTECH, INC. 2019-05-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CNR1, CNR2, HTR5A HTR2A 6/4885HTR2C 8/4885HTR2B 11/4885
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME HTR7, HTR2C, HTR1A HTR2A 8/4885HTR2C 2/4885HTR2B 7/4885
US-20250353808-A1 5-METHOXYMETHYL AND 5-HYDROXYMETHYL PHENETHYLAMINES HTR5A, PNMT, HTR6 HTR2A 8/4885HTR2C 7/4885HTR2B 17/4885
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same HTR7, HTR2C, HTR1A HTR2A 8/4885HTR2C 2/4885HTR2B 7/4885
US-20240166618-A1 PHENALKYLAMINES AND METHODS OF MAKING AND USING THE SAME PNMT, HTR6, HTR2C HTR2A 11/4885HTR2C 3/4885HTR2B 23/4885
US-20240190819-A1 Neuroplastogens and Non-Hallucinogenic Serotonin 5-HT2A Receptor Modulators HTR2A, HTR2C, HTR1A HTR2A 1/4885HTR2C 2/4885HTR2B 5/4885
US-20240124397-A1 METHODS OF TREATING PSYCHOLOGICAL DISORDERS THROUGH THE ADMINISTRATION OF SEROTONIN 5-HT2C RECEPTOR MODULATORS HTR2C, HTR2A, HTR3B HTR2A 2/4885HTR2C 1/4885HTR2B 4/4885
US-12012380-B1 Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators HTR2A, HTR2C, HTR1A HTR2A 1/4885HTR2C 2/4885HTR2B 5/4885
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR HTR2C, HTR2A, HTR3B HTR2A 2/4885HTR2C 1/4885HTR2B 4/4885
US-20230265045-A1 PHENALKYLAMINES AND METHODS OF TREATING MOOD DISORDERS PNMT, HTR2C, HTR2A HTR2A 3/4885HTR2C 2/4885HTR2B 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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