SCHEMBL29280522

SCHEMBL29280522

O=C(O)c1c(C(=O)O)c(C(=O)O)c2c(-c3ccncc3)cccc2c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 4/20 0.41
IMPDH2 P12268 2/20 0.39
HTT P42858 1/20 0.38
PIK3CD O00329 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPK14 Q16539 1/20 0.38
GAA P10253 1/20 0.38
NAPRT Q6XQN6 1/20 0.37
CYP3A4 P08684 1/20 0.36
CYP2C8 P10632 1/20 0.36
CYP2C9 P11712 1/20 0.36
HTR6 P50406 1/20 0.36
ANO1 Q5XXA6 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TNF P01375 1/20 0.36
FOLH1 Q04609 1/20 0.36
IKBKB O14920 1/20 0.35
CHUK O15111 1/20 0.35
IKBKE Q14164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29280518 0.90 IKBKB (0.40) DHODHIMPDH2HTTIKBKBCHUK
SCHEMBL8109600 0.75 HNF4A (0.49) DHODHHTTPIK3CDALDH1A1CYP3A4
SCHEMBL28774020 0.73 MEN1 (0.49) ALDH1A1HSD17B10
SCHEMBL26259561 0.72 PIK3CD (0.61) IMPDH2HTTPIK3CDALDH1A1MAPK14
SCHEMBL9170208 0.72 CA12 (0.52) DHODHALDH1A1NAPRTHSD17B10
SCHEMBL471836 0.70 NR4A1 (0.50) ALDH1A1NAPRTHSD17B10
SCHEMBL31401751 0.70 NR4A1 (0.50) ALDH1A1NAPRTHSD17B10
SCHEMBL28288595 0.69 LMNA (0.47) DHODHALDH1A1GAACYP3A4CYP2C8
SCHEMBL29105027 0.69 ALDH1A1 (0.49) DHODHHTTALDH1A1GAACYP3A4
SCHEMBL28866295 0.68 TSHR (0.44) DHODHALDH1A1MAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117757097-A Three-dimensional cobalt metal organic complex and preparation method and application thereof 南京晓庄学院 2024-03-26 CN claimed
CN-117757097-A Three-dimensional cobalt metal organic complex and preparation method and application thereof 南京晓庄学院 2024-03-26 CN disclosed
CN-117757097-A Three-dimensional cobalt metal organic complex and preparation method and application thereof 南京晓庄学院 2024-03-26 CN disclosed