SCHEMBL29280562

SCHEMBL29280562

Cc1ccccc1NC1c2ccccc2-c2ccc(C)c(C)c21

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPT P10636 4/20 0.38
NPSR1 Q6W5P4 2/20 0.38
ALOX15 P16050 1/20 0.37
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
HTT P42858 2/20 0.35
TP53 P04637 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
HPGD P15428 2/20 0.34
POLB P06746 2/20 0.34
BCHE P06276 2/20 0.34
ACHE P22303 2/20 0.34
ATM Q13315 1/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29040922 0.85 CYP2A6 (0.42) ALDH1A1MAPTNPSR1ALOX15NPC1
SCHEMBL17515219 0.83 KMT2A (0.38) ALDH1A1MAPTNPSR1KMT2AMEN1
SCHEMBL27957155 0.83 NPC1 (0.45) ALDH1A1MAPTALOX15NPC1RAB9A
SCHEMBL28307190 0.79 RAPGEF4 (0.36) MAPTNPC1RAB9ATP53KMT2A
SCHEMBL29236243 0.79 PKM (0.36) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL28167211 0.78 KMT2A (0.35) MAPTKMT2AMEN1POLBBCHE
SCHEMBL28044961 0.76 KMT2A (0.31) KMT2AMEN1POLBBCHEACHE
SCHEMBL27957148 0.74 CYP1A2 (0.45) ALDH1A1MAPTNPC1RAB9ATP53
SCHEMBL19675665 0.72 GPR3 (0.36) ALDH1A1NPSR1NPC1RAB9AKMT2A
SCHEMBL29145678 0.72 HTR2A (0.36) NPSR1KMT2AMEN1POLBBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112430189-B Pyrene organic electroluminescent material containing aromatic amine substitution 北京夏禾科技有限公司 2024-03-29 CN disclosed