SCHEMBL29280760

SCHEMBL29280760

BrCc1ccccc1-c1ccccc1.c1ccc(C(c2ccccc2)(c2ccccc2)n2cnnn2)cc1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
DPP4 P27487 1/20 0.35
KCNA5 P22460 1/20 0.33
KCNH2 Q12809 1/20 0.33
HTR7 P34969 2/20 0.32
KMT2A Q03164 1/20 0.31
NOTUM Q6P988 1/20 0.31
TACR1 P25103 2/20 0.31
PLA2G2A P14555 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132120 0.81 ALDH1A1 (0.36) ALDH1A1NPSR1
SCHEMBL198143 0.80 NOTUM (0.45) ALDH1A1NPSR1CYP11B1CYP11B2KCNH2
SCHEMBL4876723 0.75 NOTUM (0.38) ALDH1A1NPSR1CYP11B1CYP11B2KMT2A
SCHEMBL31163822 0.72 DPP4 (0.60) ALDH1A1CYP11B1CYP11B2DPP4KCNA5
SCHEMBL471 0.72 DPP4 (0.60) ALDH1A1CYP11B1CYP11B2DPP4KCNA5
SCHEMBL27726199 0.71 ALDH1A1 (0.55) ALDH1A1NPSR1CYP11B1CYP11B2DPP4
SCHEMBL2902236 0.71 DPP4 (0.58) ALDH1A1CYP11B1CYP11B2DPP4KCNA5
SCHEMBL28800470 0.69 AGTR1 (0.40) ALDH1A1
Phenylboronic Acid SCHEMBL988758 0.69 CA4 (0.44) ALDH1A1NPSR1CYP11B1CYP11B2NOTUM
SCHEMBL3858551 0.69 AGTR1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117813073-A Cosmetic compositions and methods ELC管理有限责任公司 2024-04-02 CN disclosed