Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29207934 | 0.89 | KMT2A (0.45) | POLBKMT2AHTR2AHTR2C | |
| Trifluoroacetic Acid SCHEMBL29220442 | 0.88 | KMT2A (0.42) | SMN1; SMN2KMT2ALMNATSHRHTR2A | |
| Trifluoroacetic Acid SCHEMBL29208051 | 0.87 | HTR2A (0.42) | KMT2AHTR2AHTR2C | |
| Trifluoroacetic Acid SCHEMBL29208011 | 0.85 | HTR2A (0.46) | KMT2AHTR2AHTR2CHTR2B | |
| Trifluoroacetic Acid SCHEMBL29207938 | 0.84 | HRH3 (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL30832005 | 0.82 | KMT2A (0.48) | SMN1; SMN2POLBKMT2ALMNATSHR | |
| SCHEMBL30834063 | 0.81 | LMNA (0.46) | SMN1; SMN2KMT2ALMNATSHRHTR2A | |
| Trifluoroacetic Acid SCHEMBL29208017 | 0.81 | CHRM4 (0.40) | KMT2AHTR2AHTR2C | |
| SCHEMBL30832012 | 0.81 | HTR2A (0.46) | SMN1; SMN2KMT2ALMNATSHRHTR2A | |
| Trifluoroacetic Acid SCHEMBL29207949 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820199-A | Amide compound and application thereof in preparation of Sigma2 and 5HT2A inhibitors | 瀚远医药有限公司 | 2024-04-05 | — | — | CN | disclosed |