Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29207934 | 0.95 | KMT2A (0.45) | KMT2AMEN1CCR3ALDH1A1POLB | |
| SCHEMBL30832018 | 0.88 | KMT2A (0.43) | KMT2AMEN1CCR3ALDH1A1POLB | |
| SCHEMBL30831997 | 0.85 | HTR2A (0.48) | KMT2AMEN1ALDH1A1GAATSHR | |
| SCHEMBL30832012 | 0.85 | HTR2A (0.46) | KMT2ALMNATSHRSMN1; SMN2KCNH2 | |
| Trifluoroacetic Acid SCHEMBL29208021 | 0.84 | KMT2A (0.40) | KMT2AMEN1CCR3ALDH1A1POLB | |
| SCHEMBL30831994 | 0.84 | KMT2A (0.42) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL29207983 | 0.82 | HTR2A (0.49) | KMT2AKCNH2HTR2AHTR2C | |
| Trifluoroacetic Acid SCHEMBL29280883 | 0.82 | SMN1; SMN2 (0.48) | KMT2APOLBLMNATSHRSMN1; SMN2 | |
| SCHEMBL30834063 | 0.82 | LMNA (0.46) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL30832034 | 0.82 | HRH3 (0.51) | LMNATSHRSMN1; SMN2KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024067304-A1 | COMPOUND WITH INHIBITORY ACTIVITY AGAINST SIGMA2 AND 5HT2A AND USE | 瀚远医药有限公司 | 2024-04-04 | — | — | WO | disclosed |