Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26668492 | 0.89 | RAB9A (0.61) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL4672942 | 0.82 | RAB9A (0.74) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL29220453 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KMT2AHTR2CHTR2A | |
| SCHEMBL5265103 | 0.82 | RAB9A (0.73) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL1532746 | 0.81 | RAB9A (0.71) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL7733993 | 0.79 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1POLBERCC1 | |
| SCHEMBL29208001 | 0.78 | HTR2A (0.50) | SMN1; SMN2ALDH1A1HTR2CHTR2A | |
| SCHEMBL20088427 | 0.77 | GLS (0.48) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL29280884 | 0.77 | YAP1 (0.54) | SMN1; SMN2KMT2A | |
| SCHEMBL15680134 | 0.75 | RAB9A (0.82) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820199-A | Amide compound and application thereof in preparation of Sigma2 and 5HT2A inhibitors | 瀚远医药有限公司 | 2024-04-05 | — | — | CN | disclosed |