Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31383860 | 0.85 | LMNA (0.42) | LMNACHRM1ADRA1ATRPA1SLC6A2 | |
| SCHEMBL16951448 | 0.79 | LMNA (0.33) | LMNACHRM1ADRA1ATRPA1SLC6A2 | |
| SCHEMBL2477156 | 0.78 | LMNA (0.42) | LMNACHRM1ADRA1ATRPA1SLC6A2 | |
| SCHEMBL135819 | 0.78 | LMNA (0.42) | LMNACHRM1ADRA1ATRPA1SLC6A2 | |
| SCHEMBL5525837 | 0.77 | LMNA (0.50) | LMNACHRM1ADRA1ATRPA1SLC6A2 | |
| SCHEMBL20738544 | 0.77 | LMNA (0.38) | LMNACHRM1ADRA1ATRPA1SLC6A2 | |
| SCHEMBL20738712 | 0.76 | TRPA1 (0.45) | LMNACHRM1ADRA1ATRPA1SLC6A2 | |
| SCHEMBL27777980 | 0.75 | LMNA (0.39) | LMNACHRM1ADRA1ATRPA1SLC6A2 | |
| SCHEMBL26261042 | 0.74 | LMNA (0.64) | LMNACHRM1ADRA1ATRPA1SLC6A2 | |
| SCHEMBL12180459 | 0.74 | ACHE (0.48) | LMNACHRM1ADRA1ATRPA1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |