Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | HTR5A | P47898 | 2/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736593 | 0.72 | HTR5A (0.50) | TSHRNOS2NOS3HTR5A | |
| SCHEMBL10033961 | 0.63 | NPC1 (0.50) | HTR2CHTR7 | |
| SCHEMBL29955280 | 0.63 | KCNJ1 (0.49) | — | |
| SCHEMBL17132729 | 0.62 | ENPP2 (0.41) | — | |
| SCHEMBL31703623 | 0.62 | TSHR (0.95) | TSHRNOS2NOS3HTR5A | |
| SCHEMBL1194687 | 0.62 | TSHR (0.95) | TSHRNOS2NOS3HTR5A | |
| SCHEMBL8487986 | 0.62 | NOS2 (0.52) | TSHRNOS2NOS3HTR5A | |
| SCHEMBL27632016 | 0.62 | CES1 (0.41) | HTR1AHTR1DHTR2AHTR7HTR3A | |
| SCHEMBL910658 | 0.61 | ENPP2 (0.50) | — | |
| SCHEMBL2144193 | 0.61 | CLK4 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986241-A | Biphenyl derivative, pharmaceutical composition and application thereof | 武汉睿健医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |