Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114393 | 0.94 | AKR1C3 (0.47) | KEAP1PTGS2FFAR1OPRM1OPRD1 | |
| Phenyl Propionic Acid SCHEMBL23581098 | 0.87 | KEAP1 (0.66) | KEAP1PTGS2FFAR1PTGS1CXCR1 | |
| Phenyl Propionic Acid SCHEMBL8935146 | 0.87 | KEAP1 (0.66) | KEAP1PTGS2FFAR1PTGS1CXCR1 | |
| Phenyl Propionic Acid SCHEMBL29282176 | 0.83 | KEAP1 (0.70) | KEAP1FFAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL31336237 | 0.83 | KEAP1 (0.63) | KEAP1FFAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL65250 | 0.83 | KEAP1 (0.63) | KEAP1FFAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL29563859 | 0.83 | KEAP1 (0.63) | KEAP1FFAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL12002853 | 0.78 | KEAP1 (0.56) | KEAP1FFAR1SMN1; SMN2ALDH1A1MAPK1 | |
| Phenylbutanoic Acid SCHEMBL31534033 | 0.78 | SMN1; SMN2 (0.68) | KEAP1PTGS2FFAR1LMNAMAPT | |
| SCHEMBL1345726 | 0.78 | KEAP1 (0.56) | KEAP1FFAR1SMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117987431-A | Application of knock-out mhpA gene in improving L-phenylalanine yield | 河南省健康元生物医药研究院有限公司 | 2024-05-07 | — | — | CN | disclosed |