Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
| ▸ | PTPRB | P23467 | 1/20 | 0.56 |
| ▸ | CDC25A | P30304 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | PTEN | P60484 | 1/20 | 0.56 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563859 | 0.96 | KEAP1 (0.63) | KEAP1FFAR1OPRK1OPRM1OPRD1 | |
| SCHEMBL65250 | 0.96 | KEAP1 (0.63) | KEAP1FFAR1OPRK1OPRM1OPRD1 | |
| SCHEMBL31336237 | 0.96 | KEAP1 (0.63) | KEAP1FFAR1OPRK1OPRM1OPRD1 | |
| SCHEMBL30825091 | 0.89 | FFAR1 (0.56) | KEAP1FFAR1OPRK1FFAR4PTPRB | |
| SCHEMBL29185406 | 0.89 | FFAR1 (0.56) | KEAP1FFAR1OPRK1FFAR4PTPRB | |
| Sulfuric Acid SCHEMBL18729778 | 0.89 | FFAR1 (0.55) | KEAP1FFAR1OPRK1FFAR4PTPRB | |
| Phenyl Propionic Acid SCHEMBL27725915 | 0.88 | KEAP1 (0.83) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| SCHEMBL8435278 | 0.86 | FFAR1 (0.80) | KEAP1FFAR1FFAR4PTPRBCDC25A | |
| Phenyl Propionic Acid SCHEMBL29011742 | 0.86 | KEAP1 (0.79) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| SCHEMBL3717612 | 0.85 | HDAC6 (0.66) | KEAP1FFAR1OPRK1IDO1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117987431-A | Application of knock-out mhpA gene in improving L-phenylalanine yield | 河南省健康元生物医药研究院有限公司 | 2024-05-07 | — | — | CN | disclosed |