SCHEMBL31336237

SCHEMBL31336237

O=C(O)CCc1cccc(O)c1.O=C(O)CCc1cccc(O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.63
FFAR1 O14842 5/20 0.61
PTPRB P23467 1/20 0.59
CDC25A P30304 1/20 0.59
CDC25B P30305 1/20 0.59
PTEN P60484 1/20 0.59
PTPMT1 Q8WUK0 1/20 0.59
DRD2 P14416 1/20 0.57
DRD1 P21728 1/20 0.57
TAAR1 Q96RJ0 1/20 0.57
OPRK1 P41145 2/20 0.55
IDO1 P14902 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
CHRM2 P08172 1/20 0.52
CHRM1 P11229 1/20 0.52
CHRM3 P20309 1/20 0.52
PLA2G4A P47712 1/20 0.51
FFAR4 Q5NUL3 1/20 0.50
OPRM1 P35372 1/20 0.50
OPRD1 P41143 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65250 1.00 KEAP1 (0.63) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL29563859 1.00 KEAP1 (0.63) KEAP1FFAR1PTPRBCDC25ACDC25B
Phenyl Propionic Acid SCHEMBL29282176 0.96 KEAP1 (0.70) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL30825091 0.93 FFAR1 (0.56) KEAP1FFAR1PTPRBCDC25ACDC25B
Sulfuric Acid SCHEMBL18729778 0.93 FFAR1 (0.55) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL29185406 0.93 FFAR1 (0.56) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL3717612 0.89 HDAC6 (0.66) KEAP1FFAR1DRD2DRD1TAAR1
SCHEMBL70271 0.87 KEAP1 (0.74) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL1049248 0.87 HDAC6 (0.67) DRD2DRD1TAAR1HDAC6
SCHEMBL30303107 0.87 HDAC6 (0.67) DRD2DRD1TAAR1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113009122-B Methods and systems for determining the risk of autism spectrum disorder 美国控股实验室公司 2025-01-17 CN disclosed