SCHEMBL65250

SCHEMBL65250

O=C(O)CCc1cccc(O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.63
FFAR1 O14842 5/20 0.61
PTPRB P23467 1/20 0.59
CDC25A P30304 1/20 0.59
CDC25B P30305 1/20 0.59
PTEN P60484 1/20 0.59
PTPMT1 Q8WUK0 1/20 0.59
DRD2 P14416 1/20 0.57
DRD1 P21728 1/20 0.57
TAAR1 Q96RJ0 1/20 0.57
OPRK1 P41145 2/20 0.55
IDO1 P14902 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
CHRM2 P08172 1/20 0.52
CHRM1 P11229 1/20 0.52
CHRM3 P20309 1/20 0.52
PLA2G4A P47712 1/20 0.51
FFAR4 Q5NUL3 1/20 0.50
OPRM1 P35372 1/20 0.50
OPRD1 P41143 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31336237 1.00 KEAP1 (0.63) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL29563859 1.00 KEAP1 (0.63) KEAP1FFAR1PTPRBCDC25ACDC25B
Phenyl Propionic Acid SCHEMBL29282176 0.96 KEAP1 (0.70) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL30825091 0.93 FFAR1 (0.56) KEAP1FFAR1PTPRBCDC25ACDC25B
Sulfuric Acid SCHEMBL18729778 0.93 FFAR1 (0.55) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL29185406 0.93 FFAR1 (0.56) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL3717612 0.89 HDAC6 (0.66) KEAP1FFAR1DRD2DRD1TAAR1
SCHEMBL70271 0.87 KEAP1 (0.74) KEAP1FFAR1PTPRBCDC25ACDC25B
SCHEMBL1049248 0.87 HDAC6 (0.67) DRD2DRD1TAAR1HDAC6
SCHEMBL30303107 0.87 HDAC6 (0.67) DRD2DRD1TAAR1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1047 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-4646452-A1 FLAME RETARDANT COPOLYMER WITH ONE OR MORE NON-VIRGIN FOSSIL COMPONENTS AND METHODS OF MAKING THE SAME Indorama Ventures Public Company Ltd (TH) 2025-11-12 EP claimed
CN-119985745-A Detection method for micromolecular phenolic substances and application thereof 北京中医药大学 2025-05-13 CN claimed
CN-119936223-A Metabolic marker for diagnosing or monitoring gastric cancer, screening method and application thereof 武汉迈特维尔医学科技有限公司 2025-05-06 CN claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US claimed
CN-113009122-B Methods and systems for determining the risk of autism spectrum disorder 美国控股实验室公司 2025-01-17 CN claimed
CN-119291059-A Screening method for metabolic markers for distinguishing non-colorectal cancer diseases from colorectal cancer and application of screening method 哈尔滨脉图精准技术有限公司 2025-01-10 CN claimed
US-20240369563-A1 BIOMARKER COMBINATION FOR ASSESSING RISK OF ADENOMA AND COLORECTAL CANCER, AND USE THEREOF HUMAN METABOLOMICS INSTITUTE, INC. (CN) 2024-11-07 US claimed
WO-2024178621-A1 USE OF COMPOUNDS IN PREVENTING AND/OR TREATING OBESITY OR NAFLD Westlake University (CN) 2024-09-06 WO claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
WO-2011002995-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHODS OF MAKING AND USE THEREOF KEMPHARM, INC. (US) 2011-01-06 WO claimed
US-20110002991-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHOD OF MAKING AND USE THEREOF ALTER DOMUS (US) LLC 2011-01-06 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
WO-2010097412-A1 IONIC LIQUID SOLVENTS DUBLIN CITY UNIVERSITY (IE) 2010-09-02 WO claimed
EP-2223915-A1 Ionic liquid solvents Dublin City University (IE) 2010-09-01 EP claimed
US-7452938-B2 Aqueous resin composition, aqueous coating material containing the composition, coating provided by the material, and metal plate coated with the material TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-11-18 US claimed
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2003-10-23 US claimed
US-4994273-A Solubility modulated drug delivery device MERCK & CO., INC. (US) 1991-02-19 US claimed
US-4946686-A Solubility modulated drug delivery system MERCK & CO., INC. (US) 1990-08-07 US claimed
EP-0193475-A1 Process for the acetoacetylation of aromatic compounds RHONE-POULENC CHIMIE (FR) 1986-09-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same NCEH1, HMGCR, DBH KEAP1 155/4885FFAR1 301/4885PTPRB 3107/4885
US-20110002991-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHOD OF MAKING AND USE THEREOF CYP7A1, CYP2B6, CYP2D6 KEAP1 836/4885FFAR1 307/4885PTPRB 1473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.