Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006543 | 1.00 | ROCK2 (0.49) | ROCK2ROCK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29283823 | 0.91 | ROCK2 (0.55) | ROCK2ROCK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31006528 | 0.91 | ROCK2 (0.55) | ROCK2ROCK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29283860 | 0.88 | HSP90AB1 (0.46) | ROCK2ROCK1MAPTALDH1A1GRM2 | |
| SCHEMBL31006542 | 0.88 | HSP90AB1 (0.46) | ROCK2ROCK1MAPTALDH1A1GRM2 | |
| SCHEMBL29283809 | 0.87 | THRB (0.45) | ROCK2ROCK1MAPTALDH1A1TDP1 | |
| SCHEMBL31006540 | 0.85 | THRB (0.43) | ROCK2ROCK1MAPTALDH1A1GRM2 | |
| SCHEMBL29283814 | 0.85 | THRB (0.43) | ROCK2ROCK1MAPTALDH1A1GRM2 | |
| SCHEMBL31006544 | 0.85 | LMNA (0.46) | ROCK2ROCK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29283799 | 0.85 | LMNA (0.46) | ROCK2ROCK1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |