SCHEMBL29285259

SCHEMBL29285259

Brc1cc(Br)cc(Oc2ccc(-c3cccc4c3Cc3ccccc3-4)cc2)c1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.38
GSTP1 P09211 1/20 0.37
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
EGFR P00533 1/20 0.32
HTR7 P34969 1/20 0.32
HTR2B P41595 1/20 0.32
MCL1 Q07820 3/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PRCP P42785 1/20 0.31
ABL1 P00519 1/20 0.30
ABCB1 P08183 1/20 0.30
BCR P11274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28389597 0.90 PNMT (0.35) PNMTGSTP1NPC1RAB9AEGFR
SCHEMBL28846439 0.85 GSTP1 (0.47) PNMTGSTP1NPC1RAB9APRCP
SCHEMBL3553779 0.82 PNMT (0.46) PNMTNPC1RAB9AEGFRHTR7
SCHEMBL21880049 0.81 LTA4H (0.46) PNMTGSTP1NPC1RAB9AHTR7
SCHEMBL28415829 0.81 NCOA1 (0.47) PNMTGSTP1NPC1RAB9AHTR7
SCHEMBL7520992 0.80 PNMT (0.47) PNMTNPC1RAB9AEGFRHTR7
SCHEMBL29009013 0.80 PNMT (0.41) PNMTGSTP1NPC1RAB9AHTR7
SCHEMBL7642850 0.80 MAOB (0.53) PNMTGSTP1NPC1RAB9AKDM4E
SCHEMBL29285260 0.78 RAB9A (0.44) PNMTGSTP1NPC1RAB9AHTR7
SCHEMBL28022311 0.77 SRD5A2 (0.49) GSTP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118276403-A Photoresist underlayer composition and method of forming electronic device 罗门哈斯电子材料有限责任公司 2024-07-02 CN disclosed