SCHEMBL29288010

SCHEMBL29288010

N=C(N)NCCCCCC(NC(=N)N)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 6/20 0.40
MAOB P27338 6/20 0.40
NAAA Q02083 2/20 0.40
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
EPHX2 P34913 4/20 0.38
CCR3 P51677 1/20 0.38
MAOA P21397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17887512 0.81 HRH1 (0.52)
SCHEMBL8619040 0.78 ITGB3 (0.52)
SCHEMBL25265872 0.76 AOC3 (0.47)
SCHEMBL7355421 0.74 TACR3 (0.38) CYP1A2EPHX2
Chlorobenzene SCHEMBL28349421 0.74 MEN1 (0.47) NAAAMEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL14368141 0.74 RIPK1 (0.49) EPHX2
SCHEMBL23116507 0.74 LMNA (0.38) MAOA
SCHEMBL27287608 0.74 ITGB3 (0.46) CYP1A2SMN1; SMN2
SCHEMBL28214176 0.73 TACR3 (0.44) NAAACYP1A2SMN1; SMN2
Hydrochloric Acid SCHEMBL5400591 0.73 RIPK1 (0.47) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113440437-A Stain-removing and whitening toothpaste and preparation method thereof 淮北凯乐生物科技有限公司 2021-09-28 CN disclosed