Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27287608 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL12259092 | 0.79 | ITGB3 (0.68) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL29288010 | 0.78 | KDM1A (0.40) | — | |
| SCHEMBL7351702 | 0.78 | PLA2G10 (0.43) | ITGB3ITGA2B | |
| SCHEMBL7099770 | 0.76 | ITGB3 (0.47) | ITGB3ITGA2BHDAC6HDAC3HDAC4 | |
| SCHEMBL22198637 | 0.76 | NPY4R (0.46) | — | |
| SCHEMBL8617351 | 0.75 | CHRNB2 (0.53) | ITGB3ITGA2BLMNATSHR | |
| SCHEMBL7100423 | 0.75 | ITGB3 (0.61) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL5488598 | 0.74 | CHRNB2 (0.57) | ITGB3ITGA2B | |
| SCHEMBL5489872 | 0.74 | CHRNB2 (0.57) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050421-A1 | ANALGESIC PEPTIDOMIMETIC COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-11-12 | — | — | WO | disclosed |