Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | G6PD | P11413 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9894437 | 0.77 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL30672492 | 0.75 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL29288019 | 0.75 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL25663120 | 0.71 | MAPT (0.80) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL9893973 | 0.71 | NPC1 (0.59) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL6259007 | 0.68 | ELANE (0.47) | ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL15315963 | 0.68 | KDM4E (0.46) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL514425 | 0.65 | AVPR1A (0.68) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL19244954 | 0.65 | CYP2A6 (0.49) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10432252 | 0.64 | ALDH1A1 (0.55) | MAPTALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109348715-A | pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2019-02-15 | — | — | CN | claimed |