Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787452 | 0.75 | CHEK1 (0.54) | ALDH1A1GAASHMT2RAB9ANPC1 | |
| Oxalic Acid SCHEMBL29288244 | 0.71 | NOTUM (0.41) | ALDH1A1GAASHMT2RAB9ANPC1 | |
| SCHEMBL23529963 | 0.69 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30987739 | 0.68 | KDM4E (0.44) | ALDH1A1GAAHSP90AB1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL28786717 | 0.67 | ALDH1A1 (0.42) | ALDH1A1KDM4EGLAMEN1KMT2A | |
| SCHEMBL26454605 | 0.66 | ALDH1A1 (0.38) | ALDH1A1GAASHMT2RAB9ANPC1 | |
| SCHEMBL18578596 | 0.65 | HSP90AB1 (0.41) | ALDH1A1GAASHMT2RAB9ANPC1 | |
| SCHEMBL24606617 | 0.63 | ERCC1 (0.40) | ALDH1A1GAAKDM4EHPGDCYP3A4 | |
| SCHEMBL22836610 | 0.63 | MAOB (0.45) | ALDH1A1RAB9ANPC1KDM4EHPGD | |
| SCHEMBL12985876 | 0.62 | CYP11B2 (0.47) | ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105078993-B | A kind of indazole compounds composition and its preparation method and application | 浙江大果生物医药科技有限公司 | 2019-02-22 | — | — | CN | disclosed |