Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30195988 | 0.86 | ALDH1A1 (0.38) | POLBTSHRCASP1CASP7SMN1; SMN2 | |
| SCHEMBL16637942 | 0.80 | KDM4E (0.35) | POLBTSHRCASP1CASP7SMN1; SMN2 | |
| SCHEMBL3339137 | 0.79 | HSD17B10 (0.39) | LMNAPOLBAMY1AMEP1BTSHR | |
| SCHEMBL16637747 | 0.79 | POLB (0.33) | LMNAPOLBTSHRCASP1CASP7 | |
| Ammonia Solution, Strong SCHEMBL28142626 | 0.78 | HSD17B10 (0.38) | LMNAPOLBAMY1AMEP1BTSHR | |
| SCHEMBL28823865 | 0.76 | RAPGEF4 (0.38) | LMNAPOLBMEP1BTSHRCASP1 | |
| SCHEMBL8215092 | 0.76 | CA2 (0.42) | POLBAMY1ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28029394 | 0.75 | MAPT (0.41) | LMNAPOLBTSHRKDM4EALDH1A1 | |
| SCHEMBL31124728 | 0.75 | POLB (0.33) | LMNAPOLBMEP1BTSHRCASP1 | |
| SCHEMBL16039242 | 0.75 | MAPT (0.41) | LMNAPOLBAMY1ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107980042-B | Aryldihydro-2H-benzo [ b ] [1,4] oxazine sulfonamides and related compounds as ROR gamma agonists and for the treatment of disease | 莱斯拉公司 | 2021-10-08 | — | — | CN | disclosed |