Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17994177 | 0.87 | NOTUM (0.48) | NOTUMNPSR1NPC1RAB9ATP53 | |
| SCHEMBL29291077 | 0.85 | ALOX12 (0.40) | NOTUMNPC1SMN1; SMN2HPGDPTGER1 | |
| SCHEMBL29291074 | 0.85 | ALDH1A1 (0.39) | NOTUMNPC1RAB9ATP53SMN1; SMN2 | |
| Ethoxycarbonyl Group SCHEMBL27606185 | 0.81 | NPSR1 (0.38) | NOTUMNPSR1NPC1RAB9ATP53 | |
| SCHEMBL28221375 | 0.76 | NOTUM (0.72) | NOTUMNPC1RAB9ATP53HPGD | |
| SCHEMBL28227304 | 0.71 | NOTUM (0.42) | NOTUMNPC1RAB9ATP53POLB | |
| SCHEMBL23997326 | 0.71 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL30578709 | 0.71 | KMT2A (0.44) | NOTUMNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23997494 | 0.71 | HRH3 (0.38) | — | |
| SCHEMBL29291078 | 0.71 | AKT1 (0.36) | NPC1RAB9ATP53SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705054-A | The thioether sulfone compound and its preparation method and application of one class preventing and control Banana Root nematode | 贵州大学 | 2019-05-03 | — | — | CN | claimed |
| CN-109705054-A | The thioether sulfone compound and its preparation method and application of one class preventing and control Banana Root nematode | 贵州大学 | 2019-05-03 | — | — | CN | disclosed |