Bromobenzene

Bromobenzene

SCHEMBL29291356

Brc1ccccc1.C1CCOC1.CCOCC

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP2A13 Q16696 1/20 0.35
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.33
KDM4E B2RXH2 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HSP90AA1 P07900 1/20 0.31
NTSR1 P30989 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromobenzene SCHEMBL14795351 0.84 ALDH1A1 (0.58) ALDH1A1TDP1CYP2A13LMNASMN1; SMN2
Bromobenzene SCHEMBL5322862 0.84 ALDH1A1 (0.58) ALDH1A1TDP1HPGDTSHRGAA
Benzene SCHEMBL11181513 0.84 ALDH1A1 (0.42) ALDH1A1TSHRKDM4E
Toluene SCHEMBL14675705 0.83 LMNA (0.42) ALDH1A1CYP2A13HPGDTSHRLMNA
Bromobenzene SCHEMBL129999 0.82 ALDH1A1 (0.55) ALDH1A1TDP1CYP2A13LMNASMN1; SMN2
Bromobenzene SCHEMBL5103436 0.82 ALDH1A1 (0.55) ALDH1A1TDP1HPGDTSHRGAA
Anisole SCHEMBL2868566 0.80 CA4 (0.50) ALDH1A1TSHRLMNASMN1; SMN2GAA
Trifluoromethylbenzene SCHEMBL28383246 0.77 ALDH1A1 (0.47) ALDH1A1HPGDTSHRSMN1; SMN2GAA
Tetrahydrofuran SCHEMBL3966212 0.77 ALDH1A1 (0.50) ALDH1A1TSHRLMNAGAA
Tetrahydrofuran SCHEMBL139042 0.77 ALDH1A1 (0.50) ALDH1A1TSHRLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109232199-B Synthesis method of 1-chloro-2- (4-ethoxybenzyl) -4-iodobenzene 南京红杉生物科技有限公司 2021-11-30 CN disclosed