Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.73 |
| ▸ | NR1H3 | Q13133 | 18/20 | 0.73 |
| ▸ | SOD1 | P00441 | 1/20 | 0.60 |
| ▸ | POLA1 | P09884 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29295121 | 0.87 | NR1H2 (0.56) | NR1H2NR1H3SOD1POLA1 | |
| Podocaric Acid SCHEMBL14389445 | 0.86 | NR1H2 (0.80) | NR1H2NR1H3SOD1POLA1 | |
| Podocaric Acid SCHEMBL160062 | 0.86 | NR1H2 (0.80) | NR1H2NR1H3SOD1POLA1 | |
| Podocaric Acid SCHEMBL32474685 | 0.86 | NR1H2 (0.80) | NR1H2NR1H3SOD1POLA1 | |
| Podocaric Acid SCHEMBL6311820 | 0.86 | NR1H2 (0.80) | NR1H2NR1H3SOD1POLA1 | |
| Podocaric Acid SCHEMBL31181390 | 0.86 | NR1H2 (0.80) | NR1H2NR1H3SOD1POLA1 | |
| Podocaric Acid SCHEMBL6312979 | 0.85 | NR1H2 (0.78) | NR1H2NR1H3SOD1POLA1 | |
| SCHEMBL20561234 | 0.85 | NR1H2 (0.76) | NR1H2NR1H3SOD1 | |
| SCHEMBL2993726 | 0.85 | NR1H2 (0.76) | NR1H2NR1H3SOD1 | |
| SCHEMBL6312669 | 0.84 | NR1H2 (1.00) | NR1H2NR1H3SOD1POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883926-B1 | BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDE DERIVATIVES AND PROTEIN CONJUGATES THEREOF FOR USE AS LXR AGONISTS | REGENERON PHARMA (US) | 2024-07-10 | — | — | EP | disclosed |