Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31367969 | 0.87 | KMT2A (0.36) | PDE3BPDE3AIRAK4KMT2ATSHR | |
| SCHEMBL31367971 | 0.87 | KMT2A (0.38) | PDE3BPDE3AIRAK4KMT2ATSHR | |
| SCHEMBL29295115 | 0.83 | NLRP3 (0.40) | PDE3BPDE3APIK3R1PIK3CAIRAK4 | |
| SCHEMBL31367976 | 0.82 | KMT2A (0.41) | IRAK4KMT2ATSHRALDH1A1MEN1 | |
| SCHEMBL31367997 | 0.79 | PDE3B (0.38) | PDE3BPDE3APIK3R1PIK3CAIRAK4 | |
| SCHEMBL31367983 | 0.76 | SCD (0.37) | PDE3BPDE3AHTR2AHTR2CHTR2B | |
| SCHEMBL29294901 | 0.76 | NLRP3 (0.45) | PDE3BPDE3APIK3R1PIK3CAIRAK4 | |
| SCHEMBL31367998 | 0.75 | POLB (0.39) | KMT2ATSHRALDH1A1MEN1 | |
| SCHEMBL31367991 | 0.73 | ADORA3 (0.36) | KMT2APDE2AMEN1 | |
| SCHEMBL29294075 | 0.72 | NLRP3 (0.49) | PDE3BPDE3AIRAK4KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092051-A1 | NLRP3 MODULATORS AND USE THEREOF | Bioentropy Inc. (US) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092051-A1 | NLRP3 MODULATORS AND USE THEREOF | NLRP3, NLRP1, NOD1 | PDE3B 428/4885PDE3A 354/4885PIK3R1 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.