SCHEMBL29296299

SCHEMBL29296299

CC(C)(C)C1CCN(CC(F)F)C(=O)CC1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PER2 O15055 11/20 0.41
CRY2 Q49AN0 4/20 0.41
PIK3CD O00329 2/20 0.33
GFER P55789 1/20 0.32
USP19 O94966 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29296300 0.73 MAPT (0.35)
SCHEMBL29299316 0.73 PIK3CD (0.30) PIK3CD
SCHEMBL20001263 0.70 PER2 (0.46) PER2CRY2
SCHEMBL20001284 0.66 FPR1 (0.49) PER2CRY2
SCHEMBL19988409 0.66 POLB (0.40) PER2CRY2
SCHEMBL2032257 0.64 PIK3CD (0.64) PER2CRY2PIK3CD
SCHEMBL12776296 0.61 GFER (0.55) PIK3CDGFER
SCHEMBL29296183 0.61
SCHEMBL22142088 0.60 RIPK2 (0.31)
SCHEMBL22142526 0.60 RIPK2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF TP53, HRAS, KRAS PER2 4282/4885CRY2 3132/4885PIK3CD 932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.