Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PER2 | O15055 | 10/20 | 0.37 |
| ▸ | CRY2 | Q49AN0 | 5/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988429 | 0.69 | MMP2 (0.34) | FPR1FPR2 | |
| SCHEMBL25664012 | 0.65 | POLB (0.59) | POLBPER2CRY2DPP4CHRM2 | |
| SCHEMBL25664011 | 0.65 | POLB (0.59) | POLBPER2CRY2DPP4CHRM2 | |
| SCHEMBL14370058 | 0.65 | POLB (0.59) | POLBPER2CRY2DPP4CHRM2 | |
| SCHEMBL26750314 | 0.65 | BRD4 (0.48) | — | |
| SCHEMBL2034220 | 0.62 | PER2 (0.35) | POLBPER2 | |
| SCHEMBL2034553 | 0.60 | POLB (0.34) | POLBPER2 | |
| SCHEMBL17904507 | 0.60 | POLB (0.57) | POLBPER2DPP4 | |
| SCHEMBL2032257 | 0.60 | PIK3CD (0.64) | PER2CRY2CHRM2CHRM4CHRM5 | |
| SCHEMBL21846675 | 0.60 | PIK3CD (0.41) | POLBPER2CRY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10265310-B2 | 6-membered cyclic amines or lactames substituted with urea and phenyl | Grünenthal GmbH (DE) | 2019-04-23 | — | — | US | disclosed |
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | POLB 2568/4885PER2 268/4885CRY2 261/4885 |
| US-10265310-B2 | 6-membered cyclic amines or lactames substituted with urea and phenyl | FPR2, FPR1, FPR3 | POLB 2568/4885PER2 268/4885CRY2 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.