Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | GPR6 | P46095 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928449 | 0.93 | GPR6 (0.46) | FAAHGPR6ALDH1A1MEN1KMT2A | |
| SCHEMBL2925605 | 0.93 | FAAH (0.40) | FAAHGPR6ALDH1A1MEN1KMT2A | |
| SCHEMBL2931360 | 0.92 | GPR6 (0.47) | FAAHGPR6 | |
| SCHEMBL2931169 | 0.92 | OGA (0.38) | FAAHGPR6MEN1KMT2ALMNA | |
| SCHEMBL2930506 | 0.91 | GPR6 (0.38) | GPR6ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3049811 | 0.91 | MEN1 (0.42) | FAAHALDH1A1MEN1KMT2APHGDH | |
| SCHEMBL2929411 | 0.91 | ADORA2A (0.41) | ALDH1A1MEN1KMT2AHTTGAA | |
| SCHEMBL2927982 | 0.89 | ADORA2B (0.47) | FAAHALDH1A1MEN1KMT2APHGDH | |
| SCHEMBL2931204 | 0.89 | GPR6 (0.47) | FAAHGPR6 | |
| SCHEMBL1761022 | 0.88 | FAAH (0.58) | FAAHALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027132-B1 | THIAZOLO-PYRAMIDINE / PYRIDINE UREA DERIVATIVES AS ADENOSINE A2B RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-09-15 | — | — | EP | claimed |