SCHEMBL29308151

SCHEMBL29308151

CC(F)(F)COC(=O)C1C2CC3CC(C2)CC1C3

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.34
EPHX1 P07099 1/20 0.33
HSD11B1 P28845 3/20 0.33
FABP7 O15540 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
CCR6 P51684 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
FKBP1A P62942 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12768995 0.82
SCHEMBL10137653 0.82 LMNA (0.30)
SCHEMBL10137646 0.82 HSD11B1 (0.40) EPHX2HSD11B1
SCHEMBL685928 0.80 SLC6A3 (0.31)
SCHEMBL10150478 0.80 PPM1B (0.44) EPHX2HSD11B1ALDH1A1CYP1A2CYP3A4
SCHEMBL12357093 0.79 HSD11B1 (0.34) HSD11B1
SCHEMBL12769004 0.79 HSD11B1 (0.40) HSD11B1ALDH1A1CYP2C9L3MBTL1
SCHEMBL10169615 0.79 SLC6A3 (0.30)
SCHEMBL12016474 0.79 HSD11B1 (0.30) HSD11B1FABP7
SCHEMBL16213975 0.78 ALDH1A1 (0.34) EPHX2EPHX1HSD11B1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12038689-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed