Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23861369 | 0.76 | MEN1 (0.46) | TDP1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL476990 | 0.75 | CTNNB1 (0.51) | ADRB2CTNNB1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8585605 | 0.73 | CTNNB1 (0.45) | ADRB2CTNNB1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28268958 | 0.72 | ALDH1A1 (0.41) | TDP1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8963452 | 0.66 | KEAP1 (0.60) | TDP1CYP2C19ESR1ESR2 | |
| SCHEMBL5699549 | 0.65 | AKR1B1 (0.57) | TDP1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28376007 | 0.65 | ESR1 (0.55) | TDP1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL808870 | 0.64 | TDP1 (0.53) | CTNNB1TDP1HPGDCYP1A2CYP2C9 | |
| SCHEMBL6437231 | 0.64 | CYP2C19 (0.50) | TDP1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2596077 | 0.64 | TDP1 (0.48) | CTNNB1TDP1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084227-B1 | THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-09-29 | — | — | EP | disclosed |