Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.58 |
| ▸ | MAOB | P27338 | 10/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 1/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449734 | 0.89 | HRH3 (0.59) | MAOAMAOBHRH3CA2CA5A | |
| SCHEMBL18983602 | 0.89 | HRH3 (0.59) | MAOAMAOBHRH3CA2CA5A | |
| SCHEMBL6420814 | 0.87 | MAOA (0.65) | MAOAMAOBHRH3L3MBTL1 | |
| SCHEMBL17026485 | 0.87 | MAOA (0.61) | MAOAMAOBHRH3L3MBTL1 | |
| SCHEMBL3759785 | 0.84 | MAOB (0.74) | MAOAMAOBHRH3TOP1GSTP1 | |
| SCHEMBL2314862 | 0.81 | MAOB (0.74) | MAOAMAOBHRH3ALOX5TOP1 | |
| SCHEMBL5040852 | 0.79 | MAOB (0.57) | MAOAMAOBHRH3 | |
| SCHEMBL30468506 | 0.79 | MAOB (0.57) | MAOAMAOBHRH3 | |
| SCHEMBL29051778 | 0.79 | MAOB (0.57) | MAOAMAOBHRH3 | |
| SCHEMBL2939021 | 0.78 | MAOB (0.67) | MAOAMAOBHRH3TOP1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037328-B2 | Compounds containing benzo[d][1,3]oxathiole, benzo[d][1,3]oxathiole 3-oxide or benzo[d][1,3]oxathiole 3,3-dioxide and methods/uses thereof as agonists of G protein-coupled receptor 119 | PRAMANA PHARMACEUTICALS INC. (CA) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037328-B2 | Compounds containing benzo[d][1,3]oxathiole, benzo[d][1,3]oxathiole 3-oxide or benzo[d][1,3]oxathiole 3,3-dioxide and methods/uses thereof as agonists of G protein-coupled receptor 119 | GPR119, GPR3, GPR39 | MAOA 2368/4885MAOB 1703/4885HRH3 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.