Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.45 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21386360 | 0.83 | SRC (0.52) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19825999 | 0.80 | SMN1; SMN2 (0.46) | POLBNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7211903 | 0.80 | AOC3 (0.61) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20902076 | 0.79 | POLB (0.45) | POLBTHRBTHRALPLLIPG | |
| SCHEMBL20799661 | 0.79 | THRA (0.52) | POLBTHRBTHRAHPGDALDH1A1 | |
| SCHEMBL12350073 | 0.79 | THRA (0.52) | POLBTHRBTHRA | |
| SCHEMBL15093809 | 0.78 | HRH3 (0.65) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17637655 | 0.78 | LMNA (0.58) | POLBTHRBNPC1RAB9AHPGD | |
| SCHEMBL17244567 | 0.78 | SMYD3 (0.45) | — | |
| SCHEMBL23350825 | 0.77 | RAB9A (0.40) | POLBHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3773735-B1 | CONJUGATE OF CYTOTOXIC DRUG AND PRODRUG FORM OF SAID CONJUGATE | SYNDIVIA (FR) | 2024-07-10 | — | — | EP | disclosed |