Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 3/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24451796 | 0.84 | HTR2A (0.40) | ALDH1A1CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25691218 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTR2AHTR2CHTR6QDPR | |
| SCHEMBL29310322 | 0.80 | HTR1D (0.50) | CYP2D6CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL17660611 | 0.78 | HTR2A (0.40) | CYP2D6CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL14924095 | 0.77 | HTR2A (0.43) | ALDH1A1CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11977022 | 0.77 | TLR9 (0.44) | HTR2AHTR2CHTR6QDPRCHRNB2 | |
| SCHEMBL29310081 | 0.76 | DRD2 (0.42) | ALDH1A1CYP2D6CYP3A4HTR2AHTR2C | |
| SCHEMBL24123870 | 0.73 | SLC9A1 (0.43) | CYP2D6CYP3A4CYP2C9HTR2AHTR2C | |
| SCHEMBL29310093 | 0.73 | DRD2 (0.42) | ALDH1A1CYP2D6CYP3A4HTR2AHTR2C | |
| SCHEMBL20883813 | 0.72 | HTR1D (0.38) | HTR2CHTR6CHRNB2CHRNA4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | WEE1, WEE2, DCLRE1B | ALDH1A1 3226/4885CYP2D6 4055/4885CYP1A2 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.