Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360586 | 0.76 | MAPT (0.33) | MAPTKMT2AL3MBTL1MEN1OGG1 | |
| SCHEMBL1360975 | 0.76 | OGG1 (0.35) | MAPTKMT2AL3MBTL1MEN1OGG1 | |
| SCHEMBL1701447 | 0.74 | CYP1A2 (0.55) | KMT2AMEN1CYP1A2ALDH1A1GAA | |
| SCHEMBL11440603 | 0.70 | CYP1A2 (0.51) | KMT2AMEN1CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL1360976 | 0.70 | L3MBTL1 (0.35) | MAPTKMT2AL3MBTL1MEN1S1PR2 | |
| SCHEMBL10875381 | 0.69 | GAA (0.56) | KMT2AMEN1TDP1CYP1A2GAA | |
| SCHEMBL6982295 | 0.68 | S1PR2 (0.44) | MAPTKMT2AL3MBTL1MEN1S1PR2 | |
| SCHEMBL1360614 | 0.66 | ATAD2 (0.45) | MAPTKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL1359907 | 0.66 | PDE1C (0.42) | MAPTALDH1A1HPGDCYP2C9CYP2C19 | |
| SCHEMBL17923137 | 0.66 | CRHR1 (0.35) | MAPTKMT2AMEN1S1PR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638928-B1 | N-ALKYNYL-2-(SUBSTITUTED ARYLOXY)ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES | SYNGENTA LTD (GB) | 2010-09-29 | — | — | EP | disclosed |
| EP-1638928-A1 | N-ALKYNYL-2-(SUBSTITUTED ARYLOXY)ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES | Syngenta Limited (GB) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004108663-A1 | N-ALKYNYL-2- (SUBSTITUTED ARYLOXY) ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-12-16 | — | — | WO | disclosed |