Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838703 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL11418047 | 0.73 | CYP11B2 (0.38) | ALDH1A1MAPTDRD2DRD3 | |
| SCHEMBL29789782 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTCHRNA7 | |
| SCHEMBL1011335 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTCHRNA7 | |
| SCHEMBL23811488 | 0.70 | DRD2 (0.33) | DRD2DRD3 | |
| SCHEMBL23649716 | 0.70 | HTR2A (0.33) | ALDH1A1MAPTCHRNB2CHRNA4 | |
| SCHEMBL21708059 | 0.69 | CNR2 (0.38) | DRD2DRD3 | |
| SCHEMBL31569421 | 0.69 | CYP2D6 (0.46) | CYP2D6DRD2DRD3CHRNA7 | |
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL103669 | 0.69 | — | — | |
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL29617701 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |