Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 12/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314167 | 0.84 | POLQ (0.37) | POLQNPSR1GAATSHRHTT | |
| SCHEMBL29314183 | 0.83 | GAA (0.30) | NPSR1GAA | |
| SCHEMBL29314181 | 0.83 | GAA (0.33) | POLQNPSR1GAA | |
| SCHEMBL29314127 | 0.83 | POLQ (0.41) | POLQNPSR1GAACYP3A4KDM4E | |
| SCHEMBL29313208 | 0.71 | POLQ (0.36) | POLQ | |
| SCHEMBL29314130 | 0.69 | RORC (0.34) | POLQNPSR1GAAKDM4EALDH1A1 | |
| SCHEMBL29314388 | 0.67 | POLQ (0.50) | POLQNPSR1GAATSHRHTT | |
| SCHEMBL29314384 | 0.66 | POLQ (0.52) | POLQNPSR1GAATSHRHTT | |
| SCHEMBL29314831 | 0.65 | POLQ (0.42) | POLQGAATSHRKDM4EALDH1A1 | |
| SCHEMBL30847596 | 0.65 | POLQ (0.50) | POLQNPSR1GAATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |