Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 18/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109430 | 0.81 | MET (0.45) | METPDE3BPDE3ACYP2C9PDE10A | |
| SCHEMBL22109393 | 0.81 | SYK (0.46) | CSF1RMETLDHALDHB | |
| SCHEMBL22109397 | 0.80 | LDHA (0.48) | CSF1RMETLDHALDHB | |
| SCHEMBL21167414 | 0.79 | MET (0.53) | METPDE3BPDE3ACYP2C9PDE10A | |
| SCHEMBL29318098 | 0.78 | LDHA (0.42) | METLDHALDHB | |
| SCHEMBL21167610 | 0.78 | MET (0.54) | METPDE3BPDE3ACYP2C9PDE10A | |
| SCHEMBL21167397 | 0.77 | MET (0.46) | METPDE3BPDE3ACYP2C9PDE10A | |
| SCHEMBL21167616 | 0.76 | MET (0.55) | METPDE3BPDE3ACYP2C9PDE10A | |
| SCHEMBL22475958 | 0.76 | MET (0.42) | METPDE3BPDE3ACYP2C9PDE10A | |
| SCHEMBL22475671 | 0.76 | MET (0.44) | METPDE3BPDE3ACYP2C9PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |