Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 8/20 | 0.41 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109393 | 0.86 | SYK (0.46) | LDHALDHBSYKATRMET | |
| SCHEMBL29318034 | 0.85 | NPC1 (0.40) | METNPC1PDPK1KDR | |
| SCHEMBL22109397 | 0.84 | LDHA (0.48) | LDHALDHBSYKATRMET | |
| SCHEMBL29314399 | 0.83 | NPC1 (0.35) | SYKMETNPC1PDPK1KDR | |
| SCHEMBL29314135 | 0.82 | MET (0.41) | LDHALDHBSYKMETCDKL5 | |
| SCHEMBL22109643 | 0.81 | ATR (0.40) | ATRMETCDKL5 | |
| SCHEMBL29314182 | 0.78 | CSF1R (0.45) | LDHALDHBMET | |
| SCHEMBL29314357 | 0.77 | NPC1 (0.40) | METNPC1PDPK1KDR | |
| SCHEMBL29314644 | 0.76 | LDHA (0.43) | LDHALDHBSYKATRMET | |
| SCHEMBL29315094 | 0.76 | ATR (0.40) | ATRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |