Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.48 |
| ▸ | LDHB | P07195 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 6/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109393 | 0.90 | SYK (0.46) | LDHALDHBSYKATRMET | |
| SCHEMBL29314135 | 0.84 | MET (0.41) | LDHALDHBSYKMETKDR | |
| SCHEMBL29318098 | 0.84 | LDHA (0.42) | LDHALDHBSYKATRMET | |
| SCHEMBL29314832 | 0.81 | LDHA (0.50) | LDHALDHBATRMET | |
| SCHEMBL29317374 | 0.80 | MET (0.42) | ATRMET | |
| SCHEMBL29314182 | 0.80 | CSF1R (0.45) | LDHALDHBMETCSF1R | |
| SCHEMBL29317471 | 0.79 | NPC1 (0.43) | SYKMETKDRNPC1 | |
| SCHEMBL1163132 | 0.77 | NPC1 (0.53) | SYKMETKDRNPC1 | |
| SCHEMBL29314644 | 0.76 | LDHA (0.43) | LDHALDHBSYKATRMET | |
| SCHEMBL12939261 | 0.76 | NPC1 (0.46) | SYKMETKDRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2020124060-A1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA, INC. (US) | 2020-06-18 | — | — | WO | disclosed |