SCHEMBL2931429

SCHEMBL2931429

C#Cc1c[nH]c(=O)nc1N

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPYD Q12882 1/20 0.42
CHUK O15111 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
5-Bromouracil SCHEMBL28990994 0.82 DPYD (0.51) DPYD
SCHEMBL28928674 0.82 CHUK (0.32) CHUK
SCHEMBL3825045 0.80 CHUK (0.45) DPYDCHUK
SCHEMBL21295321 0.74 KDM4E (0.31)
SCHEMBL5822570 0.73 TLR7 (0.31)
SCHEMBL8676844 0.73 PTPN11 (0.37)
SCHEMBL3485208 0.73 TLR8 (0.34)
SCHEMBL2043792 0.72
SCHEMBL5143009 0.72
SCHEMBL4606082 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713485-A2 SEQUENCING ADAPTERS FOR METHYLATION SEQUENCING Foundation Medicine, Inc. (US) 2026-03-25 EP claimed
US-20250320496-A1 MODULATION OF ABCB11 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-10-16 US claimed
EP-4627084-A1 MODULATION OF SYNGAP1 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS Camp4 Therapeutics Corporation (US) 2025-10-08 EP claimed
US-20250290072-A1 MODULATION OF SYNGAP1 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-09-18 US claimed
US-20250250575-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-08-07 US claimed
US-20250243488-A1 METHODS OF MODULATING PROGRANULIN EXPRESSION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-07-31 US claimed
WO-2024119145-A9 MODULATION OF SYNGAP1 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION (US) 2025-06-19 WO claimed
EP-4536831-A2 METHODS OF MODULATING PROGRANULIN EXPRESSION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS Camp4 Therapeutics Corporation (US) 2025-04-16 EP claimed
CN-119731320-A Methods of modulating expression of granulin precursors using antisense oligonucleotides targeted to regulatory RNAs 4阵营疗法公司 2025-03-28 CN claimed
WO-2024238523-A2 SEQUENCING ADAPTERS FOR METHYLATION SEQUENCING FOUNDATION MEDICINE, INC. (US) 2024-11-21 WO claimed
EP-3157573-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. 2016-10-20 US claimed
EP-3080289-A2 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2016-10-19 EP claimed
WO-2016154040-A2 BIOSYNTHETIC LABELING AND SEPARATION OF RNA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-09-29 WO claimed
WO-2015196128-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 WO claimed
WO-2015196130-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 WO claimed
US-20150307542-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX, INC. 2015-10-29 US claimed
EP-2931319-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2015-10-21 EP claimed
WO-2015089511-A2 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-06-18 WO claimed
WO-2014093924-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2014-06-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 DPYD 250/4885CHUK 4667/4885
US-20250320496-A1 MODULATION OF ABCB11 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS ABCB11, SLC10A1, SREBF1 DPYD 2772/4885CHUK 673/4885
US-20150307542-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 DPYD 250/4885CHUK 4667/4885
US-20250250575-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CPS1, CTPS1, CTPS2 DPYD 1073/4885CHUK 1191/4885
US-20250243488-A1 METHODS OF MODULATING PROGRANULIN EXPRESSION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS GRN, SNRPE, UPF1 DPYD 2827/4885CHUK 2657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.