Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313855 | 0.90 | POLQ (0.37) | POLQTDP1 | |
| SCHEMBL29314307 | 0.85 | GAA (0.32) | GAAPOLQ | |
| SCHEMBL29314318 | 0.84 | — | — | |
| SCHEMBL29314303 | 0.83 | POLQ (0.33) | GAAPOLQALDH1A1MAPTL3MBTL1 | |
| SCHEMBL29314305 | 0.82 | POLQ (0.30) | POLQ | |
| SCHEMBL31009122 | 0.78 | POLQ (0.36) | POLQ | |
| SCHEMBL29313854 | 0.78 | POLB (0.31) | TDP1 | |
| SCHEMBL29314114 | 0.76 | POLQ (0.32) | GAAPOLQALDH1A1TDP1 | |
| SCHEMBL29313853 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL29313852 | 0.75 | POLQ (0.41) | POLQALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |