Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314117 | 0.88 | POLQ (0.31) | POLQ | |
| SCHEMBL29314123 | 0.82 | ALDH1A1 (0.34) | POLQGAAALDH1A1MEN1KMT2A | |
| SCHEMBL29314118 | 0.78 | POLQ (0.33) | POLQGAAMCOLN3 | |
| SCHEMBL29313855 | 0.78 | POLQ (0.37) | POLQPOLBAPOBEC3GTDP1 | |
| SCHEMBL29314308 | 0.76 | GAA (0.32) | POLQGAAALDH1A1TDP1 | |
| SCHEMBL29314122 | 0.75 | CRHR1 (0.34) | POLQGAAMCOLN3ALDH1A1POLB | |
| SCHEMBL29314125 | 0.73 | SMN1; SMN2 (0.40) | POLQGAAALDH1A1POLBTDP1 | |
| SCHEMBL29314119 | 0.73 | CRHR1 (0.36) | POLQGAAMEN1KMT2A | |
| SCHEMBL29314130 | 0.72 | RORC (0.34) | POLQGAAMCOLN3ALDH1A1POLB | |
| SCHEMBL29314124 | 0.68 | SMN1; SMN2 (0.40) | POLQGAAALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |