Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.32 |
| ▸ | MET | P08581 | 7/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.30 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109644 | 0.90 | ABCB1 (0.36) | ABCB1ABCC1ABCG2TERTIRAK4 | |
| SCHEMBL29314464 | 0.81 | NPC1 (0.36) | ABCB1ABCC1ABCG2TERTMET | |
| SCHEMBL29317449 | 0.81 | ABCB1 (0.36) | ABCB1ABCC1ABCG2TERTMET | |
| SCHEMBL29314335 | 0.76 | MET (0.35) | METHDAC3KLKB1KLK1 | |
| SCHEMBL21167441 | 0.76 | PIK3CA (0.41) | ABCB1ABCC1ABCG2BRAF | |
| SCHEMBL29314565 | 0.76 | MET (0.34) | ABCB1ABCC1ABCG2TERTMET | |
| SCHEMBL22475873 | 0.75 | BRAF (0.36) | ABCB1ABCC1ABCG2METBRAF | |
| SCHEMBL22109643 | 0.75 | ATR (0.40) | MET | |
| SCHEMBL29314357 | 0.74 | NPC1 (0.40) | ABCB1ABCC1ABCG2METHDAC3 | |
| SCHEMBL24591103 | 0.74 | GRM5 (0.36) | ABCB1ABCC1ABCG2METHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |