Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.64 |
| ▸ | PARP1 | P09874 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273074 | 1.00 | ADORA3 (0.64) | ADORA3PARP1KDM4EMEN1KMT2A | |
| SCHEMBL29314496 | 0.87 | ADORA3 (0.62) | ADORA3PARP1KDM4EMEN1KMT2A | |
| SCHEMBL30577460 | 0.79 | ADORA3 (0.53) | ADORA3KDM4EALDH1A1 | |
| SCHEMBL30577534 | 0.76 | ADORA3 (0.46) | ADORA3PARP1TNKSTNKS2CHEK1 | |
| SCHEMBL31386897 | 0.76 | PARP1 (0.55) | ADORA3PARP1KDM4EKMT2AHSD17B10 | |
| SCHEMBL31552814 | 0.76 | ADORA3 (0.44) | ADORA3PARP1 | |
| SCHEMBL31386716 | 0.73 | PARP1 (0.60) | PARP1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL1920151 | 0.73 | KDM4E (0.62) | ADORA3PARP1KDM4EMEN1KMT2A | |
| SCHEMBL30577485 | 0.73 | KDM4E (0.62) | ADORA3PARP1KDM4EMEN1KMT2A | |
| SCHEMBL30756685 | 0.73 | CA5A (0.47) | ADORA3KDM4EHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | ADORA3 956/4885PARP1 244/4885KDM4E 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.