Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314565 | 0.86 | MET (0.34) | ALOX5NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL29317449 | 0.81 | ABCB1 (0.36) | NPC1ALDH1A1SMN1; SMN2HDAC6DHFR | |
| SCHEMBL29314464 | 0.79 | NPC1 (0.36) | NPC1ALDH1A1HDAC6DHFRCYP1A2 | |
| SCHEMBL29314367 | 0.77 | HDAC6 (0.38) | ALOX5NPC1HDAC6NOTUMHDAC4 | |
| SCHEMBL21167441 | 0.76 | PIK3CA (0.41) | NPC1RAB9AMEN1KMT2APDE10A | |
| SCHEMBL22109644 | 0.73 | ABCB1 (0.36) | NPC1HDAC6DHFRHDAC3KLKB1 | |
| SCHEMBL24591103 | 0.72 | GRM5 (0.36) | NPC1ALDH1A1SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL24591153 | 0.72 | GSK3A (0.39) | NPC1RAB9AALDH1A1ALOX15HTT | |
| SCHEMBL24591142 | 0.72 | PLK1 (0.48) | ALDH1A1HDAC6HDAC3KLKB1KLK1 | |
| SCHEMBL22475873 | 0.71 | BRAF (0.36) | NPC1ALDH1A1MEN1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |