Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317449 | 0.89 | ABCB1 (0.36) | METABCB1ABCC1ABCG2TERT | |
| SCHEMBL29314464 | 0.87 | NPC1 (0.36) | METABCB1ABCC1ABCG2TERT | |
| SCHEMBL29314533 | 0.86 | ALOX5 (0.39) | ALOX5NPC1DHFRMEN1ALDH1A1 | |
| SCHEMBL21167441 | 0.82 | PIK3CA (0.41) | ABCB1ABCC1ABCG2NPC1MEN1 | |
| SCHEMBL22109644 | 0.80 | ABCB1 (0.36) | METABCB1ABCC1ABCG2TERT | |
| SCHEMBL24591103 | 0.78 | GRM5 (0.36) | METABCB1ABCC1ABCG2NPC1 | |
| SCHEMBL24591153 | 0.77 | GSK3A (0.39) | METNPC1ALDH1A1RAB9ABRAF | |
| SCHEMBL22475873 | 0.77 | BRAF (0.36) | METABCB1ABCC1ABCG2NPC1 | |
| SCHEMBL22475725 | 0.76 | KDR (0.41) | METDHFRALDH1A1SMN1; SMN2HDAC3 | |
| SCHEMBL29314519 | 0.76 | ABCB1 (0.33) | METABCB1ABCC1ABCG2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |