Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 6/20 | 0.37 |
| ▸ | LPL | P06858 | 4/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847591 | 1.00 | CES2 (0.39) | CES2LIPELPLLIPGPDE4A | |
| SCHEMBL17903423 | 0.87 | LIPE (0.35) | CES2LIPE | |
| SCHEMBL31207708 | 0.87 | LIPE (0.35) | CES2LIPE | |
| SCHEMBL837370 | 0.85 | LIPE (0.39) | LIPELPLLIPGPDE4APDE4B | |
| SCHEMBL19031772 | 0.83 | LPL (0.45) | LPLLIPGF2F11PRSS1 | |
| SCHEMBL29909454 | 0.83 | PDE2A (0.39) | LIPELPLLIPGPDE4APDE4B | |
| SCHEMBL20536870 | 0.83 | LPL (0.45) | LPLLIPGF2F11PRSS1 | |
| SCHEMBL4108381 | 0.83 | PDE2A (0.39) | LIPELPLLIPGPDE4APDE4B | |
| SCHEMBL22606823 | 0.82 | LPL (0.36) | LIPELPLLIPGF2F11 | |
| SCHEMBL24596359 | 0.82 | ALDH1A1 (0.39) | LIPELPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |