Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317775 | 0.83 | MET (0.44) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29315788 | 0.81 | MET (0.40) | MET | |
| SCHEMBL29314946 | 0.78 | MET (0.45) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29314794 | 0.77 | MET (0.39) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL21167532 | 0.77 | MET (0.55) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL21167744 | 0.77 | MET (0.55) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL22109200 | 0.76 | ATR (0.39) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29314890 | 0.71 | MET (0.39) | MET | |
| SCHEMBL22109430 | 0.69 | MET (0.45) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL14378441 | 0.68 | MET (0.59) | METPDE3BPDE3APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |