Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317783 | 0.85 | MET (0.41) | METNQO2IKBKETBK1ATR | |
| SCHEMBL29317548 | 0.84 | MET (0.37) | METNQO2ATRDYRK1AJAK2 | |
| SCHEMBL29314852 | 0.81 | MET (0.45) | MET | |
| SCHEMBL20004070 | 0.80 | MET (0.41) | METNQO2DYRK1AJAK2HCRTR2 | |
| SCHEMBL29315243 | 0.79 | MET (0.34) | METNQO2DYRK1AJAK2HCRTR2 | |
| SCHEMBL25836231 | 0.78 | MET (0.38) | METNQO2DYRK1AFGFR1FGFR2 | |
| SCHEMBL22109191 | 0.78 | MET (0.38) | METNQO2DYRK1AJAK2 | |
| SCHEMBL21167598 | 0.76 | MET (0.48) | METNQO2HCRTR2 | |
| SCHEMBL22109153 | 0.75 | MET (0.72) | METNQO2 | |
| SCHEMBL29314973 | 0.73 | MET (0.60) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |