Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 14/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.62 |
| ▸ | SPR | P35270 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206530 | 0.88 | MPO (0.67) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL30877859 | 0.88 | MPO (0.67) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL2404826 | 0.87 | MPO (0.72) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| Iodide SCHEMBL26662926 | 0.85 | MPO (0.70) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| Iodide SCHEMBL30672192 | 0.85 | MPO (0.70) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL29206553 | 0.81 | MPO (0.64) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL30877838 | 0.81 | MPO (0.64) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL2404396 | 0.79 | MPO (1.00) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL2407287 | 0.79 | MPO (1.00) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL4352009 | 0.78 | MPO (0.74) | MPOSLC6A4HTR2ATRPM8HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239747-A1 | Next Generation 5-HT2AR Agonists | HUXLEY HEALTH, INC. (CA) | 2024-07-18 | — | — | US | disclosed |
| US-20240239747-A1 | Next Generation 5-HT2AR Agonists | HUXLEY HEALTH, INC. (CA) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239747-A1 | Next Generation 5-HT2AR Agonists | OPRL1, HTR2A, HTR5A | MPO 3511/4885SLC6A4 47/4885NOTUM 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.